Framed for killing a Gotham City undercover cop named James Seaborn, Harley Quinn found herself on the run from a psycho detective known only as Bishop, Seaborn's former partner, who won't rest until Harley's six feet under. Starting a new day job, as psychiatrist Dr. Jessica Seaborn (who's no relation to James, the name is her idea of a cruel joke), Harley is forced to deal with obsessed lunatics, while also trying to avoid an assortment of soldiers-for-hire and deal with the Joker, all while relentlessly tracking the fiend who framed her.
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